The long-term irrational use of antibiotics for the treatment of animals and humans is underestimated and requires further attention and research, including in Ukraine. The purpose of our study was to identify bacterial isolates and study their sensitivity to antibiotics in dogs with urinary tract inflammation. According to the statistical data of the VetForce system of the university clinic, out of 202 dogs examined in the clinic, 15 (7.43%) were found to have diseases with signs of urinary tract inflammation. It has been established that inflammatory processes of the urinary tract in dogs are caused by a large number of microorganisms, but mainly by E. coli, Streptococcus urinae, Pseudomonas aeruginosa and Staphylococcus aureus.
It was found that bacterial cystitis (the first group of animals) prevailed 1.5 times compared to the indicators of animals with urolithiasis. In dogs of the first group aged 6-12 and older than 12 years, the percentage of the disease was higher compared to the group aged 0.6 to 1.6 years by 10.2 and 22.2%, respectively.
Dogs of the second group, aged 1.6-12 years, suffering from urolithiasis (66.6%), suffer from bacterial diseases 4 times more often compared to animals aged 1.6-12 years. Streptococcus urinae, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus were isolated and identified from the urine of dogs of this group.
 It has been established that inflammatory processes of the urinary tract in dogs are caused by a large number of microorganisms, but mainly by E. coli, Streptococcus urinae, Pseudomonas aeruginosa and Staphylococcus aureus. A less common microorganism, Klebsiella pneumonia, proved to be resistant.
Antibiotics should be used rationally, taking into account that for the treatment of animals it is necessary to determine the sensitivity of the pathogen with which the animal was infected. The development of resistance in pathogens is of vital importance not only for the animal, but also for humans and the environment.
Conclusions. 1. Bacterial pathogens cause inflammatory processes of the urinary tract, which are registered mainly in German shepherds and rocker spaniels of various ages, especially in those older than 1.6 years. Bacterial cystitis prevails by 1.5 times, compared to the indicators of sick animals with urolithiasis. In dogs of the first group 6-12 and older than 12 years, the percentage of the disease was higher, compared to the group from 0.6 to 1.6 years by 10.2 and 22.2%, respectively.
Dogs aged 1.6-12 years, suffering from urolithiasis (66.6%), suffer from bacterial diseases 4 times more often compared to animals 1.6-12 years old. Streptococcus urinae, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus were isolated and identified from dog urine. In the associated form, E. coli and Streptococcus pyogenes prevailed in the urine of dogs.
The microorganism Klebsiella pneumonia was found to be resistant to amoxicillin, streptomycin, kanamycin, gentamicin and tetracycline.